Answer

Which Treatments Need LegitScript to Advertise, by Platform?

Reviewed October 12, 20266 min readBy Michael Borgia, MedScale Health

Short answer

As of October 2026, for a US telehealth brand that prescribes online: Google needs LegitScript plus its own certification for every prescription treatment, Meta needs LegitScript plus authorization for any ad that promotes the drug, Microsoft needs its own preapproval, and TikTok needs proof of FDA approval, which rules out compounded GLP-1. Unapproved peptides can't run on Google, Meta or TikTok. Therapy, lab tests and med spa procedures need no LegitScript certification. MedScale Health, a paid acquisition agency for telehealth brands and clinics, plans channels from this list.

What this means for you

  • On Google, a US telehealth brand that prescribes needs LegitScript plus Google's certification before its ads serve, whatever the treatment.
  • On Meta, ads for the service run without certification. Ads that promote the drug need LegitScript plus Meta's authorization.
  • On Microsoft, telemedicine providers selling prescription drugs need Microsoft's preapproval.
  • On TikTok, prescription medicine needs proof of FDA approval, so compounded drugs can't qualify, and controlled drugs are barred.
  • Unapproved peptides can't be advertised as products on Google, Meta or TikTok.

MedScale Health, a paid acquisition agency for telehealth brands and clinics, plans each client's channel mix around which platform will accept which treatment. As of October 2026, the list below sets that out for a US telehealth brand that prescribes online and advertises to US adults. Every entry traces to a Meta, Google, Microsoft, TikTok or LegitScript page opened on October 12, 2026; where a policy is unclear or depends on facts we can't see, the entry says check. This page is marketing guidance, not legal or medical advice. Certification, payment and platform rules change, so check the sources listed at the end before acting on a specific rule.

How to read the list

By treatment

  • GLP-1, FDA-approved brands. Meta: LegitScript + authorization. Google: LegitScript + Google. Microsoft: preapproval, and its weight loss rules bar stated amounts or rates of loss. TikTok: check; FDA proof may allow it, but TikTok's drugs policy also lists weight loss drugs among those not allowed.
  • GLP-1, compounded. Meta: LegitScript + authorization; LegitScript's checklist has a compounding addendum for this. Google: LegitScript + Google. Microsoft: preapproval, and its US rules require compounded weight loss drugs to be labeled "This is a compounded drug" or equivalent, with no suggestion of FDA approval. TikTok: not allowed, because a compounded drug has no FDA approval to show.
  • Testosterone (TRT). Meta: LegitScript + authorization. Google: LegitScript + Google. Microsoft: preapproval. TikTok: check, and plan on no; testosterone is a Schedule III controlled substance, TikTok bars controlled drugs and drugs for enhancement or performance, and its US prescription exception doesn't say it covers them.
  • ED medication. Meta: LegitScript + authorization, with ads focused on health rather than pleasure and aimed at 18 and over. Google: LegitScript + Google. Microsoft: preapproval. TikTok: check; FDA proof may allow it, but TikTok lists drugs for enhancement among those not allowed.
  • Hair loss medication. Meta: LegitScript + authorization. Google: LegitScript + Google. Microsoft: preapproval. TikTok: check; FDA proof may allow an FDA-approved drug for adults.
  • Peptides that aren't FDA-approved, such as BPC-157, TB-500 and retatrutide. Meta: not allowed; Meta needs LegitScript to promote a prescription drug, and LegitScript bars certified businesses from offering, promoting or advertising impermissible peptides. Google: not allowed when marketed as safe or effective for a condition, under its unapproved substances policy. Microsoft: check; peptides aren't on its disapproved list, but it bars experimental treatments. TikTok: not allowed without FDA approval.
  • Ketamine. Meta: LegitScript + authorization to promote ketamine; ads for the clinic and the care need none. Google: LegitScript + Google. Microsoft: preapproval. TikTok: check, and plan on no; ketamine is a Schedule III controlled substance.
  • ADHD medication. Meta: LegitScript + authorization for stimulant ads; evaluation ads need none. Google: LegitScript + Google. Microsoft: preapproval. TikTok: check, and plan on no; amphetamine, lisdexamfetamine and methylphenidate are Schedule II controlled substances.
  • Mental health therapy without prescribing. Meta: no certification; health service ads target 18 and over. Google: no certification, but Health is a sensitive category, so customer lists, remarketing and lookalikes are off. Microsoft: no certification; 18 and over, and no targeting on sensitive health information. TikTok: check; medical institutions may be allowed for adults and may need certification.
  • Addiction treatment. Meta: LegitScript plus Meta's written permission for US ads. Google: LegitScript addiction services certification plus Google's own. Microsoft: LegitScript, US only, with every URL in the ad certified. TikTok: check; its US healthcare rules don't address addiction treatment.
  • Online pharmacy. Meta: LegitScript + authorization; Meta accepts no other certifier. Google: LegitScript or NABP, plus Google. Microsoft: preapproval plus NABP or LegitScript. TikTok: proof of certification from NABP or LegitScript.
  • Lab tests. Meta: no certification named; sexual health test ads must focus on health and target 18 and over. Google: no certification for STI and fertility testing in the US, and HIV home tests must be FDA-approved. Microsoft: only at-home tests approved by regulators. TikTok: check; medical devices may need certification.
  • Med spa procedures. Meta: no certification; cosmetic procedures, injectables and fillers included, target 18 and over. Google: no certification for procedures, but bidding on drug names such as Botox needs Google's certification, and injections count as Health for targeting. Microsoft: no certification named; 18 and over. TikTok: cosmetic clinics may be allowed for adults, with fillers given as an example.

What changes for an in-person clinic

The list assumes online prescribing. LegitScript's FAQ says in-person-only clinics that don't prescribe through telemedicine or take card-not-present payments for prescription drugs are generally not eligible for Healthcare Certification. In the US, Google lets any advertiser name a prescription drug in ads and landing pages without certification, but keyword-targeting drug terms needs it. Meta limits prescription drug authorization to online pharmacies, telehealth providers and manufacturers, so an in-person clinic's Meta ads stay on the clinic and the care.

Why some entries say check

TikTok's drugs policy lists prescription drugs, controlled drugs and drugs for weight loss or enhancement as not allowed, then allows prescription drugs in the US if a regulator has approved them and the audience is adult. It doesn't say how far that exception reaches, so get written confirmation from a TikTok representative before building a campaign there. Microsoft names no rule for peptides. For ketamine, LegitScript's own FAQ says it can't predict whether a platform will approve ketamine-related ads.

What MedScale does

MedScale Health maps each client's treatments against this list before choosing channels, starts LegitScript certification first where Google or drug-named Meta ads are in the plan, and files the platform requests on the certified domain. Meta service ads can run while certification is pending. Where an entry says check, MedScale gets the platform's answer in writing before spending on it.

Common questions

01Do I need LegitScript to advertise TRT online?
For a US telehealth TRT brand, yes on Google, where telemedicine providers need LegitScript plus Google's certification, and yes on Meta for any ad that promotes testosterone. Microsoft needs its preapproval. TikTok bars controlled drugs, so plan on clinic awareness only there.
02Can compounded GLP-1 programs advertise on TikTok?
Not as a product. TikTok's US policy allows prescription medicine only with proof of approval from a regulator such as the FDA, and a compounded drug has no FDA approval to show. Meta and Google allow it after LegitScript and each platform's own approval, and Microsoft after its preapproval.
03Does a therapy practice need LegitScript to run ads?
No, if it doesn't prescribe online. Meta, Google and Microsoft name no certification for therapy services, though Google treats mental health as a sensitive category, so customer lists and remarketing are off, and every platform expects health ads to target adults.
04Can peptide clinics get LegitScript certified to advertise peptides?
Not for peptides that aren't FDA-approved or eligible for compounding. LegitScript says certified businesses may not offer, promote or advertise impermissible peptides such as BPC-157, TB-500 or retatrutide, even through a partner, and Google and TikTok bar them separately.

Sources

  1. 01Meta Advertising Standards: Drugs and Pharmaceuticalschecked October 12, 2026
  2. 02Meta Business Help Center: About Meta's Prescription Drugs advertising policychecked October 12, 2026
  3. 03Meta Advertising Standards: Health and Wellnesschecked October 12, 2026
  4. 04Meta Advertising Standards: Drug and Alcohol Addiction Treatmentchecked October 12, 2026
  5. 05Google Ads policy: Healthcare and medicines (United States location specifics)checked October 12, 2026
  6. 06Google Ads policy: Prescription drug serviceschecked October 12, 2026
  7. 07Google Ads policy: Restricted drug termschecked October 12, 2026
  8. 08Google Ads policy: Prescription drugs list (non-exhaustive)checked October 12, 2026
  9. 09Google Ads policy: Unapproved substanceschecked October 12, 2026
  10. 10Google Ads policy: Addiction serviceschecked October 12, 2026
  11. 11Google Ads policy: Health in personalized advertisingchecked October 12, 2026
  12. 12Google Ads policy: Birth control, fertility, and testingchecked October 12, 2026
  13. 13Microsoft Advertising policy: Healthcare and Pharmaceutical (updated Oct 5, 2026, United States market sections)checked October 12, 2026
  14. 14Microsoft Advertising: Disapproved Healthcare Products and Supplementschecked October 12, 2026
  15. 15Microsoft Advertising: Pharmacy and Telemedicine advertising program (preapproval form)checked October 12, 2026
  16. 16TikTok Ads policy: Healthcare and Pharmaceuticals (last updated September 2026, United States section)checked October 12, 2026
  17. 17TikTok Ads policy: Dangerous Products or Services, Drugs (last updated April 2025)checked October 12, 2026
  18. 18LegitScript (Sep 22, 2026): The Peptide Boom, Why So Many Popular Products Are Still Off-Limitschecked October 12, 2026
  19. 19LegitScript: Healthcare Certification FAQschecked October 12, 2026
  20. 20LegitScript: Certification Getting Started FAQs (applying, timeline, refunds)checked October 12, 2026
  21. 21LegitScript: Healthcare Certification Application Checklist (PDF)checked October 12, 2026
  22. 2221 CFR 1308.12, Schedule II controlled substances (eCFR)checked October 12, 2026
  23. 2321 CFR 1308.13, Schedule III controlled substances (eCFR)checked October 12, 2026

Related answers

Last reviewed October 12, 2026. Platform policies change often; we re-verify every answer quarterly.

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